Using FP 11.6.602.171 with IE 10 RTM in Windows 7 (x64), many flash apps will freeze when mouse cursor is moving over the flash area.
Disabling HW Accell in both IE10 and/or FP will not solve the problem.
I made a video to show off it happening:
https://www.youtube.com/watch?v=I3DCFTMouxw
PS: It wasn't happening with IE 10 Release Preview and flash 11.6.602.168
Edit: Looks like someone else already filled a bug for the same thing: